It has also been proposed that pantothenic acid may have an antioxidant effect that reduces low-grade inflammation, which is present in the early stages of heart disease. Low levels of CoA may prevent the breakdown and clearance of fats in the blood. This is a condition in which there is an abnormally high concentration of fat or lipids in the blood (e.g., LDL “bad” cholesterol, triglycerides), and low levels of HDL “good” cholesterol. Vitamin B5 and Healthīecause pantothenic acid helps to break down fats, it has been studied for a potential role in reducing cholesterol levels in people who have dyslipidemia. A UL has not been established for pantothenic acid, because a toxic level has not been observed from high intakes. UL: A Tolerable Upper Intake Level (UL) is the maximum daily dose unlikely to cause adverse side effects in the general population. For pregnancy and lactation, the amount increases to 6 mg and 7 mg daily, respectively. RDA: The Recommended Dietary Allowance (RDA) for men and women ages 19+ years is 5 mg daily. Bacteria in the gut can also produce some pantothenic acid but not enough to meet dietary needs. Pantothenic acid is found in a wide variety of foods. It is used to make coenzyme A (CoA), a chemical compound that helps enzymes to build and break down fatty acids as well as perform other metabolic functions, and acyl carrier protein, which is also involved in building fats. Vitamin B5, or pantothenic acid, is naturally present in foods, added to foods, and available as a supplement.
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